TOP
澳门十大信誉网赌大全欢迎您! 学校首页 智慧校园
学院人物介绍
您当前的位置: 首页  学院人物介绍
闫芳芳
发布时间:2023-11-08 作者: 浏览次数:1768

个人简介:

  闫芳芳,1993年生,山东滨州人,副教授。2022年于天津大学获理学博士学位。曾获山东省优秀学生山东省优秀毕业生国家奖学金(两次)国家励志奖学金天津大学优秀博士论文等多项荣誉。20231月,就职于澳门十大信誉网赌大全。主要从事生物分子结构的量化计算、计算机辅助药物设计、化合物与靶标蛋白互作机制的动力学模拟研究。近5年来,以独立第一作者在Journal of InfectionBriefings in Bioinformatics等期刊上发表SCI研究论文10余篇,累计影响因子127.1。担任Briefings in BioinformaticsACS Chemical NeurosciencePhysical Chemistry Chemical Physics等多个知名期刊的审稿人。

主要研究方向:

1.呕吐毒素脱毒酶的分子设计

2.植物广谱抗病机制解析和分子设计

近年来主要代表论文:

1.FangFang Yan, Feng Gao*, RBD-ACE2 binding properties in five SARS-CoV-2 variants of concern with new perspectives in the design of pan-coronavirus peptide inhibitors. Journal of Infection, 2023, 86(2): e51-e54. (IF=38.637)

2. FangFang Yan, Feng Gao*, EK1 with dual Q1004E/N1006I mutation: a promising fusion inhibitor for the HR1 domain of SARS-CoV-2. Journal of Infection, 2022, 84(4): 579-613. (IF=38.637)

3. FangFang Yan, Feng Gao*, Comparison of the binding characteristics of SARS-CoV and SARS-CoV-2 RBDs to ACE2 at different temperatures by MD simulations. Briefings in Bioinformatics, 2021, 22(2): 1122-1136. (IF=13.994人民日报科技日报人民网光明网联合早报鳳凰华人资讯网前瞻网等海内外多个新闻报道).

4. FangFang Yan, Feng Gao*, An overview of potential inhibitors targeting non-structural proteins 3 (PL pro and Mac1) and 5 (3CL pro /M pro ) of SARS-CoV-2. Computational and structural biotechnology journal, 2021, 19: 4868-4883. (IF=6.155被评为热点论文,其被引频次已进入学术领域最优秀的0.1%之列).

5. FangFang Yan, Feng Gao*, A systematic strategy for the investigation of vaccines and drugs targeting bacteria. Computational and Structural Biotechnology Journal, 2020, 18: 1525-1538. (IF=6.155)

6. FangFang Yan, Xinguo Liu*, et al., Molecular dynamics exploration of selectivity of dual inhibitors 5M7, 65X, and 65Z toward fatty acid binding proteins 4 and 5. International Journal of Molecular Sciences, 2018, 19(9): 2496.(IF=6.208)

7. FangFang Yan, Xinguo Liu*, et al., Electrostatic interaction-mediated conformational changes of adipocyte fatty acid binding protein probed by molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics, 2019, 37(14): 3583-3595.(IF=5.235)

8. FangFang Yan, Xinguo Liu*, et al., Computational revelation of binding mechanisms of inhibitors to endcellular protein tyrosine phosphatase 1B using molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics, 2018, 36(14): 3636-3650.(IF=5.235)

9. FangFang Yan, Xinguo Liu*, et al., Effect of double mutations T790M/L858R on conformation and drug-resistant mechanism of epidermal growth factor receptor explored by molecular dynamics simulations. RSC Advances, 2018, 8(70): 39797-39810. (IF=4.036)

10. FangFang Yan, Xinguo Liu*, et al., Understanding conformational diversity of heat shock protein 90 (HSP90) and binding features of inhibitors to HSP90 via molecular dynamics simulations. Chemical Biology & Drug Design, 2020, 95(1): 87-103. (IF=2.874)

11. FangFang Yan, Xinguo Liu*, et al., Binding difference of inhibitors ACD and TDZ to A-FABP revealed by molecular dynamics simulations. Journal of Atomic and Molecular Sciences, 2017, 8(3): 97-104.

12. Fangfang Yan, Feng Gao*, et al., Subpopulations, binding characteristics of RBD to ACE2 and potential inhibitors of SARS-CoV-2. 全国生物信息学与系统生物学学术大会(遴选报告), 2021.

 

联系方式:

山东省泰安市岱宗大街61,澳门十大信誉网赌大全作物遗传育种系,271018

电子邮箱: yanfangfang1511@163.com

 


版权所有@澳门十大信誉网赌大全 - 澳门十大正规老牌网赌
Baidu
sogou